Dr Sreenivas Patro Sisinthy

  Sreenivas Patro Sisinthy., M. Pharm., PhD

Programme Director - (Bachelor of Pharmacy)
School of Pharmacy


sreenivaspatro.sisinthy@taylors.edu.my
Subjects Taught
  • Pharmaceutical Formulation and Development
  • Pharmaceutical Compounding and Dispensing
  • Pharmaceutical Processing
  • Physical Pharmaceutics
  • Formulation Science​

Research Interests
  • Design and Development of Self Emulsifying Drug Delivery systems
  • Development of Nanoparticulate drug delivery systems for solubility enhancement
  • Development and Optimization of Oral Controlled Release and Mouth Fast Release Drug Delivery Systems​

Research Grant
  • "Design And Optimization Of A Self Nano Emulsifying Drug Delivery System For Oral Delivery Of Olmesartan Medoxomil Using Indigenously Available Natural Oils”. This grant was funded for Ringgit Malaysia 27,000 by Taylors University, Malaysia. (TRGS/ERFS/1/2013/SOP/003). [Principal investigator] Status: Completed
  • “Role of arjunolid acid and chebulinic acid on cardio-metabolic functioning in MyD88 dependent TLR-4 downstream signaling pathways: Therapeutic and molecular approach”. This is a flagship research grant funded by Taylors University, Malaysia for RM 480500 [Co-investigator] Status: Ongoing

Industrial Consultancy
  •  “Evaluation of Antihyperlipidemic Activity of Thia’s Essential Natural Oil”. This project was funded by Thailan Bioherbs SDN BHD, Malaysia for Ringgit Malaysia 40,000. 
  •  "Development of an enteric coated formula for the in house developed Herbal tablet”. This project is funded by InQPharm, Malaysia.
  •  “Study on the effect of Poloxamer 407 on the thermal stability of a cream base”. This project was funded by Kotra Pharma, Malaysia.

Scholarly Activities / Industry Experience
  • Guided 13 post graduate students for their research work and thesis.
  • Worked as an active member of Curriculum development of both B Pharm and M Pharm syllabus of Biju Patnaik University of Technology, Orissa, India
  • Participated and presented papers in various pharmaceutical conferences and workshops
  • Member of Research Committee, Board of Studies, Board of Examiners, Taylors University, Malaysia
  • Member, Curriculum development committee, Taylors University, Malaysia
  • External examiner to Berhampur University, India Biju Patnaik University, India,  Kakatiya University, India
  • Completed an Taylors Fundamental Research Grant project worth RM 27,000
  • Completed few industrially collaborated projects sponsored by Thiallan Bioherbs, Malaysia, InQPharm Malaysia and Kotra Pharma Malaysia.

Publications
  • Mohd Javed Qureshi, Fung Fuie Phin, Sreenivas Patro. Enhanced Solubility and Dissolution Rate of Clopidogrel by Nanosuspension: Formulation via High Pressure Homogenization Technique and Optimization Using Box Behnken Design Response Surface Methodology. Journal of Applied Pharmaceutical Sciences; 2017:7(02),106-113. 
  • Sreenivas Patro Sisinthy, Nalamolu Koteswara Rao Chin Yi Lynn Sarah, Design, Optimization and in vitro Characterization of Self-Nano Emulsifying Drug Delivery Systems of Olmesartan Medoxomil. International Journal of Pharmacy and Pharmaceutical Sciences; 2017:9(1),94-101. 
  • Sreenivas Patro Sisinthy, Chin Yi Lynn Sarah, Nalamolu Koteswara Rao. Optimization of coconut oil based self-micro emulsifying drug delivery Systems of olmesartan medoxomil by simplex centroid design. International Journal of Applied Pharmaceutics; 2016:8(4),47-52. 
  • Nalamolu Koteswara Rao,Krupavaram Bethala, Sreenivas Patro Sisinthy and Sugumaran Manickam. Antihyperglycemic and In Vivo Antioxidant Activities Of Phyllanthus Watsonii A.Shaw Roots In Streptozotocin Induced Type 2 Diabetic Rats.  International Journal of Pharmacognosy and Phytochemical Research; 2016: 8(2), 335-340. 
  • Nalamolu Koteswara Rao,Krupavaram Bethala, Sreenivas Patro Sisinthy and Sugumaran Manickam. In vivo antioxidant activity of orthosiphon stamineus in streptozotocin induced in streptozotocin induced type 2 diabetic rats. International Journal of Medical and Exercise Science; 2016:2(1), 67-74. 
  • Nalamolu Koteswara Rao, Krupavaram Bethala, Sreenivas Patro Sisinthy and Sugumaran Manickam. In vivo antioxidant activity of phyllanthus watsonii a.shaw leaves in streptozotocin induced type 2 diabetic rats. Pharmanest; 2016:7(1), 3024-3026. 
  • Sreenivas Patro Sisinthy*, Nalamolu Koteswara Rao, ME Bhanoji Rao. Controlled Release Layered Matrix Tablets of Itopride Hydrochloride:  In Vitro and In Vivo Evaluation. Asian Journal of Pharmaceutical and Clinical Research; 2015:8(6), 130-135. 
  • Sreenivas Patro Sisinthy*, Selvakumar Duraipandi, Nalamolu Koteswara Rao, ME Bhanoji Rao. Determination and Validation of a HPLC method with UV detection of Itopride Hydrochloride in Human Serum. International Journal of Pharmacy and Pharmaceutical Sciences; 2015: 7(11), 246-249. 
  • Nalamolu Koteswara Rao, Krupavaram Bethala, Sreenivas Patro Sisinthy and Kanuparthi Sharmila Rajeswari. Antidiabetic Activity of Orthosiphon Stamineus Benth Roots in Streptozotocin Induced Type 2 Diabetic Rats. Asian Journal of Pharmaceutical and Clinical Research; 2014: 1(7), 149-153. 
  • Bethala Krupavaram, Nalamolu Koteswara Rao and Sreenivas Patro Sisinthy. Herbal Remedies for Diabetes-A Review on Conventioanlly Widely Available Plants. International Journal of Inventions in Pharmaceutical Sciences; 2013: 1(3), 149-155. 
  • Yong Tze Teen, Adinarayana Gorajana, P S Rajinikanth, Sreenivas Patro Sisinthy and Nalamolu Koteswara Rao. Development and Optimization of Gastroretentive drug delivery system for Oseltamivir. International Journal of Drug Development & Research; 2013: 5(1), 197-203. 
  • Kareti Srinivasa Rao, ME Bhanoji Rao, S Sreenivas Patro and Ajay Kumar Patnaik. Development and Validation of New Analytical Method for Cefadroxil Monohydrate in Bulk and Pharmaceutical Dosage Forms. International Journal of Research and Reviews in Pharmacy and Applied Sciences; 2012: Dec 2(6) 1045-1054. 
  • KS Rao, KB Deb, MEB Rao, SS Patro and AK Patnaik. Development and Validation of Stability Indicating Analytical Method for Doxazosin Mesylate and its Application, Chemical Science Journal, 2012:CSJ-67, 1-10. 
  • Kareti Srinivasa Rao, ME Bhanoji Rao, S Sreenivas Patro and Ajay Kumar Patnaik. Development And Validation Of New Analytical Method For Ceftriaxone Sodium In Bulk And Pharmaceutical Dosage Forms, International Journal of Research and Reviews in Pharmacy and Applied Sciences;2012:  2(3).556-565 
  • Chandrasekhar Patro, S Sreenivas Patro, Bibhu Prasad Panda and ME Bhanoji Rao. Formulation and evaluation of mouth fast dissolving tablets. Der Pharmacia Lettre, 3 (4), (2011), 63-70. 
  • SS Patro, TK Panda, BVV Ravi Kumar, MEB Rao and S Santra. Spectrophotometric determination of Itopride Hydrochloride in Bulk and in Pharmaceutical Dosage Forms. Acta Ciencia Indica, Vol XXXIII C, No.3, (2007), 219-221. 
  • SS Patro, S Santra, BVV Ravi Kumar, MEB Rao and TK Panda. Spectrophotometric determination of Aceclofenac in Bulk and in Pharmaceutical Dosage Forms. Acta Ciencia Indica, Vol XXXIII C, No.3, (2007), 317-318. 
  • Saleh M Al Saidan, Yellela S R Krishnaiah, Sreenivas S Patro and Vemulapalli Satyanarayana. In Vitro and In Vivo Evaluation of Guar Gum Matrix Tablets for Oral Controlled Release of Water-soluble Diltiazem Hydrochloride. AAPS PharmSciTech 6(1), 2005, E14-E21. 
  • K Prakash, SS Patro, K Shanta Kumari and MEB Rao. HPLC method for the estimation of Diclofenac Sodium in Pharmaceutical Dosage Forms. Acta Ciencia Indica, Vol XXX C, No. 2, (2004), 135-138. 
  • KV Kanna Rao, MN Reddy, MRB Rao, SS Rao and SS Patro. Reverse Phase High Performace Liquid Chromatographic Determination of Salmeterol Xinafoate in Pharmaceutical Dosage Forms. Acta Ciencia Indica, Vol XXVII C, No. 1, (2002), 13-16. 
  • KEV Nagoji, S Srinivasa Rao, ME Bhanoji Rao and S Sreenivas Patro. Determination of Nimesulide in Dosage Formulations by Reverse Phase High Performace Liquid Chromatography. Acta Ciencia Indica, Vol XXVII C, No. 1, (2002), 59-63. 
  • KEV Nagoji, J Panda, S Srinivasa Rao and SS Patro. Determination of Nimesulide in Dosage Formulations by Reverse Phase High Performace Liquid Chromatography. Asian Journal of Chemistry, Vol 14, No. 1, (2002), 393-343. 
  • KEV Nagoji, S Vijaya Srinivas, S Srinivasa Rao and SS Patro. Simultaneous Estimation of Nimesulide and Paracetamol in Tablets by Reverse Phase High Performace Liquid Chromatography. Asian Journal of Chemistry, Vol 14, No. 1, (2002), 1004-1008. 
  • KEV Nagoji, S Vijaya Srinivas, ME Bhanoji Rao and SS Patro. Simultaneous Estimation of Diclofenac Sodium and Paracetamol in Tablets by Reverse Phase High Performace Liquid Chromatography. Acta Ciencia Indica, Vol XXVIII C, No. 3, (2002), 147-150. 
  • M Mathrusri Annapurna, KEV Nagoji, S Srinivasa Rao and SS Patro. Spectrophotometric Estimation of Metfromin Hydrochloride in Pharmaceutical Dosage Forms. Asian Journal of Chemistry, Vol 14, No. 3-4, (2002), 1775-1776. 
  • M Mathrusri Annapurna, KEV Nagoji, S Srinivasa Rao and SS Patro. Spectrophotometric Estimation of Gliclazide in Pharmaceutical Dosage Forms. Asian Journal of Chemistry, Vol 14, No. 3-4, (2002), 1775-1776. 
  • M Mathrusri Annapurna, KEV Nagoji, S Vijaya Srinivas and SS Patro. Spectrophotometric Estimation of Rifamicin in Capsules. Asian Journal of Chemistry, Vol 14, No. 3-4, (2002), 1797-1798. 
  • YSR Krishnaiah and SS Patro.  Oral Controlled Release Dosage Forms for Diltiazem Hydrochloride Pharma Times Vol. 33, February (2001). 
  • YSR Krishnaiah and SS Patro. Determination of Diltizem hydrochloride in Human Plasma by Reverse Phase High Performace Liquid Chromatography Indian Drugs Vol. 37, No. 12 (2000), 570-573.

Guest Lectures Delivered
  • Delivered Guest Lectures in different platforms on topics like “Peptide and Protein Drug Delivery” and on “Drug Targeting to Brain”

Awards & Honours
  • Gold Medalist in M Pharm from Andhra University, Visakhapatnam, India

Professional Affiliations
  • Malaysian Pharmaceutical Society
  • Controlled Release Society, Malaysia Chapter
  • Indian Pharmaceutical Association, India
  • Association of Pharmaceutical Teachers of India, India
  • Indian Hospital Pharmacists Association, India
  • Global Science and Technology Forum, Singapore